NHP Reagent Resource

NIH Nonhuman Primate Reagent Resource

NHP Reagent News Update

September 2009

The NHP Reagent Resource provides reagents for in vivo
modulation of immune responses, for in vitro diagnostic
and reference reagents designed to optimize the use of
nonhuman primates in biomedical research.

Sponsored by the National Center for Research Resources and the National Institute of Allergy and Infections Diseases, NIH

Immunophenotyping Reagents

Custom antibodies or formulations for reactivity with NHP species

CONJUGATED ANTIBODIES FOR FLOW CYTOMETRY/ CONFOCAL MICROSCOPY

Qdot™ antibodies against NHP CD4, CD8

Anti-macaque α4β7 integrin

CD4-AmCyan (L200 clone reacts with many primate species)

COMING SOON:

Anti-CXCR5 (macaque)

Anti-CD8β (rhesus)

Anti-NKp46 (rhesus)

Visit our DATABASE OF ANTIBODIES and ELISA KITS that cross react with NHP species
Over 900 commercial reagents
Reactivity with 12 NHP species
Antibodies to CDs, TCRs, Igs, cytokines, chemokines, and more
Searchable database

Antibodies and Fusion Proteins for in vivo Administration

Recombinant antibodies or fusion proteins for modulation of immune in vivo.

CELL DEPLETING ANTIBODIES

Antibodies to target and deplete CD4+ and CD8+ lymphocytes.

Also, non-depleting forms of the same recombinant antibodies.

BLOCKING OR NEUTRALIZING ANTIBODIES

Anti-CD154

Anti-CD40

Anti-α4β7

COMING SOON:

Macaque recombinant anti-CD4, anti-CD8

Anti-IL-15 (for most NHPs)

Anti-IL-10 (for most NHPs)

NHP Reference Reagents

Reference NHP cell lines, immunoglobulins, anti-immunoglobulins and transforming viruses

TRANSFORMING VIRUSES AND NHP CELL LINES

B-LCLs from most NHP species

Transformed cyno T cell line HSC-F

RECOMBINANT AND PURIFIED NHP IMMUNOGLOBULINS

Recombinant rhesus IgG1, IgG2, IgG3, IgG4

IgG from serum of most NHP species

Species-specific anti-IgG mAbs

COMING SOON:

Macaque IgG isotype-specific antibodies

Purified macaque IgA and anti-IgA antibodies.